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Pneumococcal respiratory disease and vaccines 

Pneumococcal respiratory disease and vaccines
Chapter:
Pneumococcal respiratory disease and vaccines
Source:
Acute Respiratory Infections (Oxford Respiratory Medicine Library)
Author(s):

Thomas Bewick

and Wei Shen Lim

DOI:
10.1093/med/9780199588084.003.0008

Streptococcus pneumoniae is the predominant bacterial pathogen implicated in all lower respiratory tract infections

The organism's pathogenicity is to a large extent due to its polysaccharide capsule, which also enables classification into different serotypes/serogroups

Risk factors associated with pneumococcal pneumonia include HIV infection, defects in humoral immunity, asplenia, diabetes mellitus, cancer, high alcohol intake, smoking and the extremes of age...

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