As an acute coronary syndrome is a thrombotic process all patients are immediately treated with anti-platelet agents.

Patients are monitored in a high-dependency environment and given adequate analgesia and oxygen.

In the setting of complete vessel occlusion (ST-elevation) urgent restoration of flow is achieved with thrombolytics or angioplasty.

If complete vessel occlusion has not occurred therapy is directed to reduce ischaemia and the development of further thrombus.