Part of the Oxford Psychiatry Library series, this resource is a clear and comprehensive overview of the brain science underpinning addiction that helps explain the current and future therapeutics for the range of addictions, using full colour images to enhance understanding. It focuses on the nature of addiction as a brain disorder that includes a range of different behavioural traits such as impulsivity and reward dependence, and discusses the critical role of kinetic and pharmacological factors. The also explains how the primary pharmacological targets of drugs of abuse are now understood, the relation to the variable nature of addiction to different substances, and how this may lead to new approaches to treatment.
Table of Contents
- Chapter 1 What is addiction?
- Chapter 2 Burden of addiction
- Chapter 3 Key elements of addiction
- Chapter 4 Neurobiological processes in addiction
- Chapter 5 Drug pharmacokinetics and abuse liability
- Chapter 6 Pharmacodynamics of addictive substances
- Chapter 7 The dopamine system and addiction
- Chapter 8 The GABA system and addiction
- Chapter 9 The glutamate system and addiction
- Chapter 10 The opioid system and addiction
- Chapter 11 Nicotine addiction
- Chapter 12 Appetite hormones and addiction
- Chapter 13 Conclusion and overview