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Arthroscopic Knee Surgery 

Arthroscopic Knee Surgery
Arthroscopic Knee Surgery
Acute Pain Medicine

James Flaherty

, Clint Elliot

, and Richa Wardhan


Arthroscopic knee is one of the most common outpatient orthopedic procedures. Specifically, anterior cruciate ligament (ACL) repair is a common procedure with numerous multimodal analgesia considerations. Via the example case, this chapter examines acetaminophen pharmacology and the efficacy of acetaminophen as a multimodal analgesic, including comparing its benefit with that obtained with nonsteroidal anti-inflammatory drugs. It also discusses regional anesthetic concerns related to ACT repair, the utility of regional anesthesia in the perioperative pain management of an ACL repair, and options for managing postoperative pain resulting from arthroscopic surgery. Finally, it addresses questions pertaining to pharmacogenomics and the epigenetics of acute pain management.

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