Qualified, early specialism training

This online reference is designed to help medical trainees, general prescribers, healthcare workers and students to understand how antibiotics work, to demonstrate where they might be most appropriate, and to make clear the threat of antibiotic resistance.Less

The fully revised and updated seventh edition of Antimicrobial Chemotherapy is an essential guide to the principles of antimicrobial chemotherapy, the problem of resistance and its control through policies, antimicrobial stewardship and surveillance. It provides an aid to informed, rational prescribing for common bacterial, fungal, parasitic and viral infections. Divided in five parts, this online resource addresses issues specific to both the developed and developing world. Part 1 discusses mechanisms of action and resistance to antibacterial, antifungal antiprotozoal, antiviral, and antiviral agents. Part 2 provides guidance about the problem of resistance, mechanisms of acquired resistance and genetics of resistance. Part 3 analyses the use of the laboratory, general principles of the treatment of infection, dosing in special groups (extremes of age, pregnancy, obesity), safe prescribing, prophylaxis and the role of policies in antimicrobial stewardship. Part 4 provides advice about the treatment of common infections. There are also chapters on the management of mycobacterial disease, viral infections, HIV/AIDS and parasitic infections, as well as analysis of the development and marketing of antimicrobial drugs.Less

This online resource details over 30 challenging cases from a wide area of infectious diseases, medical microbiology and virology and includes topics ranging from typhoid fever to secondary syphilis. Each case is supported by the commentary of a renowned expert in the field, allowing readers to improve their own management of these patients. Each case offers 'Clinical Tips', 'Learning Points' and 'Evidence Base' boxes to enhance the learning process along with the 'Expert Commentary', providing an inside track on how the experts approach challenging cases ranging from secondary syphilis to typhoid fever and viral haemorrhagic fever. Less

This resource, featuring numerous high-quality images and illustrations guiding diagnosis and case discussion, is meant to serve as a highly practical guide covering current approaches and new developments in the diagnosis, treatment, and management of a cross section of infectious diseases, including community-acquired and healthcare-associated infections.Less

Infectious Diseases Emergencies is a compact reference that summarizes the key topics of those infectious disease processes that are most commonly seen in emergency departments, clinics, and urgent care facilities. The opening section reviews principles of infectious disease management and general management of severe infections in acute and emergency environments. The following sections provide a “head-to-toe” synopsis of common infections presenting in both outpatient and acute care settings, including the following human areas: central nervous system; ear, nose, and throat; ocular; cardiovascular; pulmonary; gastrointestinal; genitourinary; skin and soft tissue; and bone and joint. The concluding sections discuss vector-borne infections, infections in special populations, bioterrorism, and finally antibiotic resistance. Each chapter covers some basic elements of the disease, epidemiology, diagnosis and tests, organisms involved, treatment, and other key issues. Concisely written and consistently organized chapters outline the most useful elements of diagnosis and treatment for easy memorization and clarity.Less

Antimicrobial agents either kill (bactericidal) or inhibit (bacteriostatic) the growth of a microorganism by targeting specific unique bacterial sites or metabolic pathways. Common antibiotic adverse effects and toxicities include allergic reactions, numerous possible toxicities, alteration of human flora, drug interactions, and promoting of antibiotic resistance. Presumptive and empirical therapy relies on the clinical syndrome and anatomical site of infection. Factors to consider when choosing empirical therapy include identification of the organism, the estimated benefit to the patient, the probable susceptibility of the isolated (or suspected) pathogen based on laboratory results or local epidemiological parameters, and pharmacokinetic/pharmacodynamic considerations. Host factors, including age, immune deficiency status, and other underlying conditions, should always be considered when choosing an antibiotic. There are few absolute indications for the prophylactic use of antimicrobials, and this is one area where misuse is common. The susceptibility of common pathogens is often predictable, allowing adequate empirical treatment. The main driver for the development of antibiotic resistance is the inappropriate use of antibiotics. Bacteria may be naturally resistant or may acquire resistance by means of DNA mutation or acquisition of resistance-conferring DNA from another source (e.g. plasmids). Mechanisms of antibiotic resistance include chemical modification of antibiotics, reduced uptake into cells, active efflux from cells, target site modification, overproduction of antibiotic target, and metabolic bypass of inhibited reaction. Control of resistance may be achieved through adherence to prescribing guidelines, restriction policies that reduce the use of certain antibiotics, and antimicrobial stewardship programmes.Less

Revised for its second edition to include the latest national and international guidelines, the Oxford Handbook of Expedition and Wilderness Medicine enables efficient preparation and planning before the journey, advises on camp logistics, risk management, and medical problems during the trip, as well as highlighting rare but important risks to those visiting remote areas. Focusing on preventative measures, it also contains chapters dealing with crisis management, emergency care, and evacuation from challenging environments. Now containing more guidance about the obligations of a clinician joining an expedition, and the ethical approach to such work, it also provides an increased emphasis on medicine in various extreme environments. With revised and additional illustrations, more colour plates, and an increased use of important algorithms, it has been updated with the support of the Royal Geographical Society, and incorporates the combined knowledge and experience of a team of experienced clinicians and expeditioners.Less

Reflecting the recent changes in postgraduate infection training, the Oxford Handbook of Infectious Diseases and Microbiology provides an integrated clincal infection overview. Practical and comprehensive, it builds on the first edition, covering the basics of antimicrobial therapy, bacteriology, virology, and parasitology, together with a detailed overview of clinical syndromes, diseases, and conditions. The authors are consultants in microbiology and infectious diseases in respected UK institutions and have worked together with trainees to produce a book that will be an essential companion for everyone caring for those with infection.Less

The Oxford Textbook of Infectious Disease Control discusses the issues of geographical spread of human communicable diseases. Split into six chapters it tackles surveillance, quarantine, vaccination, and forecasting for disease control. A wide selection of representative maps and diagrams are used to illustrate the ideas explored. Less

The authors are international experts in their fields, from the UK, Europe, North and South America, Asia and Australia. This book is aimed at microbiologists, research scientists, infectious diseases clinicians, respiratory physicians, and those managing immunocompromised patients, as well as mycology course students and trainees in medical microbiology and infectious diseases.Less

The Oxford Textbook of Zoonoses comprehensively provides a systematic, cross disciplinary approach to the science and control of all zoonoses - diseases naturally transmissible between vertebrate animals and man.Less

Tropical Diseases outlines the diagnosis, prevention, and treatment of diseases encountered in developing regions—areas where the unexpected can occur and where Western medical capabilities are often unavailable. Diseases profiled here include a brief historical background, main signs and symptoms, and practical methods of individual prevention and treatment. Additional features include over 60 maps depicting the geographic origins and modern distribution of tropical diseases, a classification scheme for parasitic diseases according to the location of the final parasitic stage in the human body, and clinical case studies.Less

The Tropical Medicine Notebook provides a concise overview of the key topics in tropical medicine using short notes, diagrams, maps, and tables. The book is divided into eight sections. The first five cover infections caused by bacteria, viruses, fungi, protozoa, and helminths. The following three present the topics of vector biology, disease syndromes, and envenomation. A final section listing relevant guidelines, publications, and other resources guides the reader to more detailed information when required.Less

Vaccines are an integral part of routine preventative health care for persons of all ages and play an integral role in protecting individuals against vaccine-preventable diseases. This handbook provides easy-to-understand, practical information on routinely recommended preventative vaccines for persons of all ages. It is written to be an informative, easily accessible, quick resource that addresses common vaccine issues that may be encountered by busy health-care providers in different specialties and at all different levels of training and practice. The “Did you know that” sections at the beginning of each chapter provide interesting facts on vaccines and vaccine preventable diseases. The FAQ section at the end of each chapter provides answers to commonly encountered situations in clinical practice involving vaccines. Exploring the different sections of this handbook will arm the reader with the tools needed to discuss the importance of vaccines and recommend the appropriate vaccines for their patients in order to optimally protect them against vaccine preventable diseases.Less